Glasgow Pancreatitis Prognostic Criteria

The Glasgow (Imrie) Pancreatitis Prognostic Criteria identify severe acute pancreatitis based on eight physiologic and laboratory factors assessed within 48 hours.

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Age
Serum Albumin
Arterial PO2 (Room Air)
Serum Calcium
Blood Glucose
Serum LDH
Serum Urea Nitrogen
WBC Count

Indicaciones de Uso

Used in adults with acute pancreatitis to stratify risk of severe disease within the first 48 hours. Helps identify patients likely to develop persistent organ failure, guiding early escalation of monitoring, ICU triage, and aggressive supportive care. Evidence shows Glasgow performs modestly overall but is among the better early classifiers for persistent organ failure (AUC ~0.62–0.84) 1 [Level II evidence].

Información y Precauciones

Identifies severe pancreatitis only after 48 h and performs modestly, with accuracy limited by delayed parameter availability and low sensitivity. Best early classifier among traditional scores but still AUC ~0.62–0.84 at admission 1 [Level II evidence]. Specific but misses early severe cases; no proven impact on outcomes. Should never replace clinical judgment, as multiple reviews show overall low prognostic utility of AP scores 2 [Level II evidence].