Medical News & Research

In a TriNetX retrospective cohort of 51,263 adults, levetiracetam lowered early epilepsy after severe TBI with an adjusted hazard ratio of 0.55 but showed no reduction in 1-year epilepsy and was linked to memory, metabolic, and psychiatric adverse outcomes.

Network meta-analysis of 11 RCTs with 37,443 patients found similar MACE vs 12-month DAPT but lower bleeding, with very early aspirin discontinuation under 1 month linked to higher stent thrombosis in ACS subsets.

In a single-site ethnographic study in Indiana with six weeks of observations and interviews of 20 ED clinicians, legal ambiguity led to altered questioning about self-managed abortion, intentionally limited documentation, variable reporting knowledge, and perceived risk of delayed or defensive care without strong institutional legal support.

In a phase 3 RCT of 142 adults, complete remission at 104 weeks was 37% with obinutuzumab vs 6% with tacrolimus, with similar rates of grade 3 or higher adverse events and infections.